家庭对临床风险,储存和处置剩余抗生素的知识:在七个发展中国家进行的一项跨国研究
Katia Iskandar1,2,3, Reham Kotb4,5, Michelle Cherfane3,6
1Department of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut P.O. Box 146404, Lebanon.
Antibiotics (Basel, Switzerland)
|December 30, 2025
概括
用剩余的抗生素 (SMLA) 进行自我治疗是常见的,但没有遵循安全的做法. 关于抗菌素耐药性的知识并不总是转化为安全的抗生素处理和处置.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 公共卫生政策 公共卫生政策
背景情况:
- 用剩余抗生素 (SMLA) 进行自我治疗显著促进抗菌素耐药性 (AMR),特别是在发展中国家.
- 了解抗生素使用和处理的知识与实践差距对于有效的抗菌素耐药性制策略至关重要.
研究的目的:
- 调查有关抗生素使用,储存和处置的知识和实践,在有SMLA病史的个人中进行.
- 确定七个发展中国家知识和实践的差异.
主要方法:
- 一项涉及7个国家的3191名成年人 (孟加拉国,巴西,埃及,印度,约旦,黎巴嫩,塞尔维亚) 进行的横截面研究,这些成年人曾经报告过SMLA.
- 调查问卷评估了对抗生素使用,耐药性和SMLA风险的知识,以及对储存和处置实践的评估.
主要成果:
- 参与者理论知识高于平均水平,但在安全实践方面存在重大差距,只有21.9%的参与者正确地处置剩余的抗生素.
- 32.6%的人报告了不适当的储存,而47.0%的人将抗生素丢弃在家用垃圾中.
- 更高的抗菌耐药性知识与更差的处置实践矛盾地相关 (OR = 0.97,p < 0.001).
结论:
- 存在着关键的知识与实践差距,表明仅仅理论知识无法确保安全的抗生素处理.
- 以教育为重点的抗菌素耐药性策略可能不足;干预措施必须解决超越知识缺陷的行为变化.
- 有效的策略需要考虑结构性,文化和个人健康信仰因素,以有效打击抗药性耐药性.
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