在患有后COVID综合征的个体中,氧气消耗,呼吸机械和肺部超声波之间的相关性
Jéssica Gabriela Messias Oliveira1, Samantha Gomes de Alegria1, Isabelle da Nóbrega Ferreira1
1Post-Graduation Programme in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2º andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil.
心肺运动测试 (CPX) 揭示了COVID后综合征 (PCS) 患者的功能能力受损. 年龄,BMI,肺超声波 (LUS) 和脉冲振荡计 (IOS) 与减少的峰值氧气消耗 (VO2峰值) 相对应.
科学领域:
- 肺部病理学 肺部病理学
- 心血管呼吸系统生理学
- 后COVID综合征研究研究
背景情况:
- COVID-19显著影响呼吸系统,需要长期监测COVID后综合征 (PCS) 患者的肺功能和功能能力.
- 评估运动能力对于了解COVID-19对身体功能的持续影响至关重要.
研究的目的:
- 通过心肺运动测试 (CPX) 评估PCS患者在运动期间的功能能力.
- 调查峰值氧气消耗 (VO2峰值) 与通过螺旋计,脉冲振荡计 (IOS) 和肺超声波 (LUS) 获得的参数之间的关联.
主要方法:
- 60名被诊断患有PCS的人被纳入研究.
- 进行心肺运动测试 (CPX),以测量峰值氧气消耗 (VO2峰值).
- 使用螺旋计,脉冲振荡计 (IOS) 和肺超声波 (LUS) 来评估肺功能和肺状况.
主要成果:
- 在PCS患者中,平均VO2峰值为18.4±5.9毫升/公斤/分钟,表明功能能力降低.
- 在VO2峰和年龄 (rs = -0.465),体重指数 (BMI,rs = -0.354),IOS共振频率 (rs = -0.312) 和LUS通风分数 (rs = -0.261) 之间观察到显著的负相关性.
- 更高的年龄,BMI和特定的IOS和LUS参数与PCS患者的运动能力较低有关.
结论:
- 患有PCS的患者表现出功能能力受损,这是CPX期间VO2峰值降低的证据.
- 年龄,BMI和LUS和IOS的客观测量与该人口的运动能力下降有关.
- 这些发现,利用LUS和IOS等低成本设备,为PCS监测提供了有前途的途径,需要进一步调查影响氧气消耗的因素.
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