南非的职业和女性乳腺癌死亡率:一个病例对照研究
Melitah Motlhale1, Hlologelo Ramatsoma1, Tsoseletso Maabela1
1Epidemiology and Surveillance, National Institute for Occupational Health, National Health Laboratory Service, Johannesburg 2001, South Africa.
International journal of environmental research and public health
|December 30, 2025
概括
与基本工作相比,南非妇女在各种职业中的乳腺癌死亡率更高. 需要针对高风险职业群体进行有针对性的预防和查.
科学领域:
- 流行病学 流行病学
- 职业健康 职业健康 职业健康
- 在瘤学瘤学.
背景情况:
- 乳腺癌是南非妇女癌症死亡的主要原因.
- 职业对乳腺癌死亡率的影响尚未在全国范围内进行评估.
研究的目的:
- 调查南非妇女职业和乳腺癌死亡率之间的联系.
- 为了确定特定的职业群体,提高乳腺癌死亡风险.
主要方法:
- 不匹配的病例控制研究使用2011-2019年国家死亡率数据.
- 在30岁以上的女性中,与13,207例乳腺癌死亡人数和64,849例非恶性循环系统疾病死亡人数进行了比较.
- 多变量逻辑回归调整为年龄,死亡年份,教育程度,省份和吸烟情况.
主要成果:
- 与基本职业相比,立法者,高级官员和经理,职员,专业人士,手工艺和相关行业的工人,技术人员和服务人员的乳腺癌死亡率更高.
- 在2011-2015年和2016-2019年期间,风险持续升高.
- 副职业分析显示,建筑和相关行业的工人 (不包括电工),法律,社会和文化专业人员以及商业和行政专业人员的风险特别高.
结论:
- 在南非,职业是乳腺癌死亡率的重要决定因素.
- 调查结果强调了针对特定职业群体量身定制的预防和查策略的必要性.
- 对职业暴露和乳腺癌风险的进一步研究是有必要的.
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