与氧尿素治疗相关的深层组织感染后四肢救援以及在接受氧尿素治疗的患者中对随访协议的建议
Éva Badak1,2, Edina Bodnár1,3, László Virág4,5
1Department of Dermatology, MTA Centre of Excellence, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Journal of clinical medicine
|December 30, 2025
概括
水氧尿素 (HU) 治疗可能会导致严重的皮肤,特别是在糖尿病或动脉样硬化症患者中. 一项拟议的护理方案旨在改善这些高风险患者的皮肤学随访.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 氧尿素 (HU) 是一种用于瘤治疗的细胞静止药物,已知具有皮肤副作用.
- 严重的并发症,如不愈合的,深层组织感染和骨髓炎是罕见的,但可能的.
- 患有糖尿病和动脉样硬化等并发症的患者有更高的风险.
研究的目的:
- 报告严重的HU相关病例与深层组织感染和骨髓炎.
- 突出并发症在加剧HU引起的皮肤并发症中的作用.
- 为高风险患者提出皮肤学后续检查方案.
主要方法:
- 一个患有多细胞血病的患者的病例报告,接受了HU治疗.
- 关于HU相关皮肤并发症的文献综述.
- 基于临床经验和文献的护理方案的开发.
主要成果:
- 患者患有骨髓缩和不愈合的,进展为严重的深层组织感染和骨髓炎.
- 综合系统和局部治疗导致完全治愈.
- 提出了一项皮肤病随访护理方案.
结论:
- 氧尿素可以引起严重的皮肤和深层组织并发症,特别是在糖尿病和动脉样硬化症患者中.
- 早期识别和管理对于治愈至关重要.
- 拟议的协议可能会改善接受HU治疗的高风险患者的治疗结果.
相关概念视频
Hemodialysis II: Procedure and Complications
558
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
558
Hemodialysis III: Nursing Management
681
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
681
Acute Kidney Injury VI: Nursing Management
359
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
359
Venous Thrombosis III: Interprofessional Care
257
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
257
Acute Kidney Injury V: Interprofessional Care
268
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
268
Kidney Transplant II: Surgical Procedure
277
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
277


