身体圆度指数在预测中国成年人阻断性睡眠呼吸暂停严重程度方面优于身体质量指数
Ningchang Tang1,2, Yuenan Ni1,2, Fengming Luo1,2
1Department of Respiratory and Critical Care Medicine, West China School of Medicine and West China Hospital, Sichuan University, Chengdu 610041, China.
Journal of clinical medicine
|December 30, 2025
概括
身体圆度指数 (BRI) 与严重阻塞性睡眠呼吸暂停 (OSA) 的相关性比身体质量指数 (BMI) 更强. BRI提高了严重OSA的查效率,特别是在女性和年轻人中.
科学领域:
- 医学科学 医学科学 医学科学
- 临床研究 临床研究
- 诊断工具 诊断工具
背景情况:
- 肥胖是阻塞性睡眠呼吸暂停 (OSA) 的重要危险因素.
- 身体质量指数 (BMI) 可能不能完全代表OSA风险,因为它无法解释内脏脂肪的分布.
- 身体圆度指数 (BRI) 是反映内脏脂肪的指标,需要进一步验证OSA查.
研究的目的:
- 开发和验证基于BRI的模型,用于预测严重阻塞性睡眠呼吸暂停 (OSA).
- 为了比较BRI与BMI在识别严重OSA风险方面的有效性.
主要方法:
- 追溯和前性招募接受多睡眠图 (PSG) 的患者.
- 利用最小绝对收缩和选择 (LASSO) 回归来确定严重OSA的预测因素 (呼吸暂停-呼吸暂停指数[AHI]≥30事件/小时).
- 开发并验证了结合BRI和其他相关因素的预测模型,并根据性别和年龄对子组进行分析.
主要成果:
- 总共有7579名患者被分析,其中51%被诊断为严重的OSA.
- 增加的BRI与严重OSA的更高风险显著相关 (OR2.01,p < 0.001).
- 与没有BRI的模型相比,基于BRI的模型显示出更高的预测性能 (更高的AUC),特别是在女性和50岁以下的个人中.
结论:
- 身体圆度指数 (BRI) 是一种比身体质量指数 (BMI) 更强大的严重OSA预测指标.
- 将BRI纳入预测模型可以提高中国成年人严重OSA查效率.
- 在改善女性和年轻人群体中OSA查敏感度方面,BRI特别有前途.
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