干燥的眼插座综合症-一个叙事评论
Daniele Lorenzano1, Alberto Chierigo1, Alessandra Claudia Modugno2
1Oculoplastic and Orbital Service, Department of Ophthalmology, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Journal of clinical medicine
|December 30, 2025
概括
干燥的眼底综合征 (DASS) 影响了许多人造眼睛的使用者,导致干燥和炎症. 管理需要解决诸如炎症和膜不稳定等多种因素,以获得更好的结果.
科学领域:
- 眼科医生 眼科 眼科
- 假肢眼睛护理 假肢眼睛护理
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 干眼 (Dry Anophthalmic Socket Syndrome,简称DASS) 是一种常见的,但未被认可的假眼睛佩戴者的病症.
- 症状包括干燥,不适,排泄和口炎症.
- 诊断包括症状问卷和临床迹象,如结膜染色.
研究的目的:
- 审查与DASS相关的解剖学,细胞和分子变化.
- 为了突出DASS的多因素病因.
- 强调需要全面的管理策略.
主要方法:
- 对DASS的解剖学,细胞和分子变化的文献综述.
- 分析导致DASS的因素,包括梅博米腺功能障碍和炎症.
- 检查诊断标准和管理方法.
主要成果:
- 常见的发现包括梅博米腺功能障碍,杯状细胞密度降低和结膜炎症增加 (MMP-9,ICAM-1).
- 氧化应激 (NOX4,KEAP1,NRF2失调) 在其中起作用.
- 眼的错位,假肢因素,卫生和环境都可能加剧DASS.
结论:
- DASS是多因素的,需要针对性地管理炎症,膜,机械刺激和眼的位置.
- 提高意识,标准化诊断和基于证据的协议对于假眼佩戴者至关重要.
- 解决卫生和环境因素对于症状管理也很重要.
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