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茶叶聚-铁纳米颗粒的一步合成,增强抗氧化和抗菌性能

Zhiwen Hu¹, Zhenzhen Wu^1,2, Lingxin Yu¹

¹College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

Foods (Basel, Switzerland)

|December 30, 2025

概括

研究人员开发了茶叶多铁纳米粒子 (TP-Fe NPs),以提高稳定性和生物可用性. 新型TP3-Fe1NP表现出强大的抗氧化和抗菌特性,具有出色的生物相容性,为各种应用提供双重功能.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物化学生物化学

背景情况:

茶叶多 (TPs) 具有显著的生物活性潜力,但稳定性和生物可用性不佳.
开发稳定和生物可利用的TP形式对于其实际应用至关重要.

研究的目的:

通过协调驱动的自组装来合成和表征茶叶多铁纳米粒子 (TP-Fe NPs).
评估合成TP-FeNP的抗氧化和抗菌功效.
评估TP-FeNP的生物相容性.

主要方法:

协调驱动的自组装被用来合成TP-FeNP.
描述技术包括SEM,TEM,FTIR和XRD.
使用DPPH和ABTS试验评估了抗氧化活性.
对大肠杆菌和金黄色杆菌的抗菌活性进行了测试.
使用L929细胞系评估了细胞毒性.

主要成果:

证实了稳定的TP-FeNP的成功形成,由基和碳基团介导.
TP3-Fe1NP表现出优越的抗氧化活性,具有高的DPPH (65.71%) 和ABTS (89.64%) 基因清除率.
TP3-Fe1 NPs对大肠杆菌 (91.44%) 和金黄色细菌 (88.67%) 的抗菌抑制率显著.
在测试度范围 (0.01-0.1 mg/mL) 中,TP3-Fe1 NP对L929细胞没有显著的细胞毒性.

结论:

与原生TP相比,TP-FeNP,特别是TP3-Fe1具有更高的稳定性和生物可用性.
TP3-Fe1NP具有强大的双抗氧化剂和抗菌功能.
TP3-Fe1NP的优良生物相容性支持它们作为安全有效的治疗或功能材料的潜力.

关键词:

它具有抗菌活性,具有抗菌活性.抗氧化剂活性抗氧化剂活性标志性特征的描述.绿色合成是一种绿色合成.铁是铁,铁是铁,铁是铁.纳米颗粒是一种纳米粒子.茶叶多醇是一种多醇.

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