关于口腔细菌在中风中的作用的综述
Florencia Gayo1,2, Jorge Moldes3, Susana Bravo4
1Unit of Periodontology, Faculty of Dentistry and Medicine, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain.
International journal of molecular sciences
|December 30, 2025
概括
牙周炎可能会增加中风风险. 在中风患者的样本中发现了口腔细菌及其产物,这可能会影响中风的结果和预后,尽管需要更多的研究.
科学领域:
- 口腔微生物学 口腔微生物学
- 神经学 神经学
- 心血管疾病是什么心血管疾病
背景情况:
- 牙周炎与全身炎症和血管问题有关.
- 新出现的证据表明口腔健康和中风风险之间存在联系.
研究的目的:
- 审查中风患者口腔细菌的证据.
- 评估口腔细菌对中风病理生理学,结果和预后的影响.
主要方法:
- 流行病学,血清学和分子研究的叙述性综述.
- 对口腔细菌DNA,内毒素和血液,唾液和血栓中的抗体进行分析.
主要成果:
- 对牙周病原体的血清阳性与中风风险和更差的预后有关.
- 在thrombi.com中发现的口腔细菌DNA (Streptococcus,Prevotella)
- P. gingivalis抗体与较低的反相关;其他细菌与不良事件相关.
结论:
- 这些发现支持牙周炎和缺血性中风之间的潜在联系.
- 需要使用先进的分子方法进行进一步的研究,以确认机制和病原体的存在.
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