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增加MMP9的表达-A潜力在体外生物标志物对 COMPopathies 的表达.

Helen F Dietmar1, Ella P Dennis1, Francesca M Johnson de Sousa Brito1

  • 1Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.

International journal of molecular sciences
|December 30, 2025
PubMed
概括

错误折叠的蛋白质会导致罕见的骨疾病. 研究人员确定了MMP9上调作为COMPopathies的特定标志物,有助于这些疾病的体外药物查.

关键词:
生物标志物生物标志物脑内质网膜/细胞应激压力矩阵金属蛋白质酶的结构.蛋白质的错误折叠 蛋白质的错误折叠骨发育不良症 骨发育不良症

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