水产养殖生长的分子调节:从基因到可持续生产
Dana Andreea Șerban1, Cristian-Alin Barbacariu1, Mihaela Ivancia2
1Research and Development Station for Aquaculture and Aquatic Ecology, Alexandru Ioan Cuza University Iasi, 11, Carol I Blvd., 700506 Iași, Romania.
Life (Basel, Switzerland)
|December 30, 2025
概括
可持续的水产养殖增长需要了解综合基因网络,多倍体基因组学和分子环境相互作用. 研究强调了表观遗传机制和基因编辑,以增强水生物种的生长和气候适应能力.
科学领域:
- 水产养殖是水产养殖的一种方式.
- 遗传学 是一个遗传学.
- 分子生物学分子生物学
背景情况:
- 全球水产养殖每年生产9100万,在可持续增长优化方面面临挑战.
- 目前的局限性源于对监管系统,多倍体遗传学和分子环境联系的不充分理解.
研究的目的:
- 系统地审查和综合有关水产养殖生长调节的研究.
- 确定影响生长的关键分子机制和环境相互作用.
- 确定可持续水产养殖强化研究重点.
主要方法:
- 来自四个数据库的180篇同行评审文章 (1992-2025) 的系统文献综述.
- 综合多层次网络的分析:GH-IGF轴,TGF-β/myostatin信号和表观遗传学.
- 评估多倍体基因组学和基因编辑技术,如CRISPR-Cas9.
主要成果:
- 增长调节涉及综合网络 (GH-IGF,TGF-β/myostatin,表观遗传学),以应对环境因素.
- 多化提供了遗传多样性,但也带来了繁殖挑战;CRISPR-Cas9神经静止素淘汰显示了增长增强的潜力.
- 表观遗传机制 (DNA甲基化,microRNAs) 促进了适应和跨代遗传.
结论:
- 开发适应气候变化的菌株需要整合多化繁殖,多组体和表观遗传标记.
- 可持续的强化需要协调的基础设施,协调的法规和国际合作.
- 将分子机制与实际应用相结合,对于提高可持续水产养殖生产至关重要.
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