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Updated: Jan 7, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
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由免疫细胞表型介导的棕化基因与口腔癌之间的因果关系:孟德尔的随机研究

Zhong-Hui Jiang1, Yan-Hong Wei, Hang Xie

  • 1Department of Stomatology, Shenzhen Longhua District Central Hospital, Shenzhen, China.

Medicine
|December 30, 2025
PubMed
概括

这项研究确立了棕化基因和口腔癌之间的因果关系,确定了ZDHHC2和ZDHHC24等特定基因作为风险因素. 发现免疫细胞表型调解了这种关系,为口腔癌提供了潜在的治疗点.

关键词:
门德尔的随机化免疫细胞 免疫细胞调解分析 调解分析口腔癌是指口腔癌的发生.棕细胞代谢的发生

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