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Updated: Jan 7, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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从U到mnm5Se2U:通过2-素和5-甲基胺甲基修改调基配对偏好

Paulina Kuwerska1, Katarzyna Kulik2, Karolina Podskoczyj1

  • 1Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz, 90-924, Poland.

Scientific reports
|December 30, 2025
PubMed
概括

细菌tRNA中的修饰性尿素,如2-thiouridine和2-selenouridine,会影响代码子的识别. 这项研究揭示了5-甲基胺甲基 (mnm5) 和素修饰如何影响RNA双重稳定性和基配对特异性.

关键词:
2 - 氨基氨酸是什么?2 - 氨基二酸氨基.5 - 替代的尿素.它们是Anticodon,它们是Anticodon.在 CD 里,你会看到 CD 里.修改过的寡合子核酸.酸的固体相合成合成双重复制RNA是什么意思热稳定性 热稳定性U-G 基数对的基本对.兹维特里奥尼克结构这是一个tRNARNA.

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Improving Small RNA-seq: Less Bias and Better Detection of 2'-O-Methyl RNAs08:49

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2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications05:41

2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications

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