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基于组织学的微结构组织幽灵用于现实的超声波模拟

Daniek A C van Aarle¹, Richard G P Lopata¹, Hans-Martin Schwab¹

¹Photoacoustics and Ultrasound Laboratory Eindhoven (PULS/e), Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.

Ultrasonic imaging

|December 30, 2025

概括

这项研究引入了一种使用组织微观结构创建现实的超声波模拟的新方法. 先进的数值幻影提高了超声波成像和数据生成的准确性.

科学领域:

医疗成像医学成像
生物医学工程生物医学工程
计算科学计算科学

背景情况:

超声波模拟对于传感器设计和图像分析至关重要.
由于简化了组织模型,目前的模拟缺乏现实性.
需要现实的幻影来训练数据与基础真相.

研究的目的:

开发一种用于构建现实的二维数值组织幽灵的新框架.
为了提高超声波模拟的准确性和现实性.
为了生成高准确度的超声波训练数据.

主要方法:

各种组织的组织学图像被细分为识别微观结构组件.
基于细分,声学特性 (密度,声音速度) 被空间映射出来.
一个伪光谱波溶解器被用于超声波模拟.
模拟与使用定量指标的ex vivo数据进行了验证.

主要成果:

这种新的框架成功地生成了现实的二维数值组织幽灵.
使用这些幽灵的模拟显示,与基线相比,斑点图案的现实性得到了改善.
定量分析证实了超声波模拟中的增强现实性.
与CT数据的整合显示了针对患者的超声波数据集的潜力.

结论:

开发的框架允许基于组织学数据进行准确和现实的超声波模拟.
这种方法显著提高了用于超声波研究的in silico幻影的真实性.
该方法有望为各种应用生成现实的超声波数据集.

关键词:

数据生成数据的数据生成.在模拟模型中.数字组织幻影.质地分析,质地分析.超声波模拟的超声波模拟

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