严重急性呼吸道综合征冠状病毒2感染期间的神经病变:一个病例报告
Roya Yazdani1, Farzaneh Barzkar2, Zahra Mirzaasgari3
1Department of Neurology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Journal of medical case reports
|December 30, 2025
概括
在冠状病毒疾病 (COVID-19) 的急性阶段,即使没有呼吸道症状,神经病也可能发生. 这一案例突出了SARS-CoV-2的存在.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 神经病是COVID-19已知的并发症,通常表现为像米勒-费舍尔综合征这样的延迟免疫反应.
- 然而,在COVID-19的急性传染性阶段,脑脊液 (CSF) PCR呈阳性的神经病变以前没有被记录.
研究的目的:
- 在COVID-19的急性传染阶段报告头骨神经病变病例.
- 研究神经参与急性SARS-CoV-2感染的潜在机制.
主要方法:
- 一个53岁妇女的病例报告显示,她患有阴,双眼和头痛.
- 诊断评估包括SARS-CoV-2的鼻和脑脊液 (CSF) 聚合酶链反应 (PCR).
- 治疗包括雷梅西维尔和皮质类固醇.
主要成果:
- 该患者在鼻和脑脊液样本中检测出SARS-CoV-2阳性.
- 在急性感染期间观察到的神经症状,包括,双眼和头痛.
- 患者的神经症状在接受雷梅西维尔和皮质类固醇治疗后有所改善.
结论:
- 神经症状可以在SARS-CoV-2感染的急性阶段表现出来,可能是由于直接的病毒入侵或二次免疫介导损伤.
- 临床医生应将COVID-19视为神经干扰的潜在原因,即使没有典型的呼吸道或全身症状.
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