在印度患者中,将甲状腺功能障碍与慢性病联系起来
Gayathri Chelamkuri1, Nalugotla Lakshmanna1, Vadlamudi Chandramohan2
1Department of Biochemistry, Kurnool Medical College, Kurnool, Andhra Pradesh, India.
Bioinformation
|December 30, 2025
概括
慢性病显著影响甲状腺功能,65.56%的患者显示甲状腺异常. 这凸显了在脏疾病管理中对甲状腺疾病的临床关注的需要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 慢性病 (CKD) 与复杂的代谢障碍有关.
- 在CKD患者中,垂体-甲状腺轴和外围甲状腺激素代谢可能会受到显著的影响.
- 甲状腺功能障碍是脏疾病患者的已知的并发症.
研究的目的:
- 为了调查诊断为慢性病的患者甲状腺异常的患病率.
- 为了检查功能标志物和甲状腺生物标志物在CKD患者之间的关系.
主要方法:
- 进行了一项横截面研究,涉及90名被诊断为慢性病的患者.
- 分析了血液参数,包括尿素,肌素和甲状腺生物标志物.
- 用皮尔森的相关性来评估血清甲状腺刺激激素和估计的膜过率之间的关系.
主要成果:
- 观察到甲状腺异常的高患病率,影响研究参与者的65.56% (90人中59人).
- 在血清甲状腺刺激激素水平和估计的膜过率 (r=-0.04,P=0.001) 之间发现了显著的负相关性.
- 甲状腺生物标志物的变化在CKD患者组中很常见.
结论:
- 甲状腺功能障碍在患有慢性脏病的患者中普遍存在并具有临床意义.
- 这些发现强调了监测甲状腺功能在CKD管理中的重要性.
- 对这些甲状腺疾病的认识可以帮助临床医生为患有脏疾病的人提供更好的患者护理.
相关概念视频
Chronic Kidney Disease I: Introduction
531
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
531
Chronic Kidney Disease III: Interprofessional Care
316
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
316
Chronic Kidney Disease II: Clinical Manifestations
516
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
516
Chronic Kidney Disease IV: Nursing Management
283
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
283
Acute Kidney Injury IV: Diagnostic Studies and Prevention
238
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
238
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
158
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
158


