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修改玻璃离子体水泥的抗菌效果和压力强度

Kalyana Ponangi¹, Satish Venkata Sarvepalli², Anil Kumar Enkeshwarlu James³

¹Noble Community Clinics, Wautoma, Wisconsin, USA.

|December 30, 2025

概括

将抗菌剂添加到玻璃离子体水泥 (GIC) 中,提高了其抗菌性能,但降低了其压力强度. 抗生素修改的GIC在测试材料中显示出有效性和强度的最佳平衡.

科学领域:

牙科材料科学牙科材料科学
生物材料工程生物材料工程
微生物学微生物学

背景情况:

玻璃离子水泥 (GIC) 是一种常见的牙科修复材料.
将抗菌剂纳入GIC可以损害其物理性质.
需要在修改后的GIC中平衡抗菌疗效与机械完整性.

研究的目的:

为了评估与各种抗菌剂修改的FUJI IX GIC的抗菌功效和压力强度.
为了比较赫西丁, cetrimide, triclosan 和抗生素组合对 GIC 特性的影响.
为了确定修改后的GIC是否可以保持足够的物理性质,同时表现出抗菌活性.

主要方法:

富士IX GIC被修改为2%的赫西丁,1%的 cetrimide,2.5%的 triclosan 或1.5%的抗生素 (metronidazole,minocycline,ciprofloxacin).
使用通用测试机器,在圆柱形标本上测试了压力强度.
抗菌疗效被评估使用阿加扩散方法在BHI阿加,测量抑制区.

主要成果:

与对照组相比,所有修改后的GIC都显示出抗菌活性.
与对照组相比,所有修改后的GIC都显著降低了压力强度.
经过抗生素修改的GIC组在实验组中显示出优越的抗菌疗效和压力强度.

结论:

用抗菌剂修改GIC增强了抗菌性质,但损害了压力强度.
抗生素修饰的GIC为开发具有改善抗菌功能的GIC提供了一个有前途的方法.
需要进一步的研究,以优化配方,以增强机械性能与抗菌活性一起.

关键词:

玻璃离子体水泥的玻璃离子体抗菌功效抗菌功效抗菌功效压力强度的压力强度是什么

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