拉丁美洲的炎症性皮肤病:治疗挑战和机会
Luis Daniel Mazzuoccolo1, Maria Valeria Angles1, Maria Eugenia Cappetta1
1Department of Dermatology, Hospital Italiano de Buenos Aires, University Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Journal of inflammation research
|December 30, 2025
概括
像牛皮和亚托邦性皮肤炎这样的炎症性皮肤疾病在拉丁美洲很普遍,但意识和治疗机会仍然很低. 改善护理需要区域合作和政策改革,以获得公平的结果.
科学领域:
- 皮肤病学和免疫学
- 公共卫生和流行病学.
- 卫生经济学和卫生政策
背景情况:
- 慢性免疫媒介性炎症性皮肤疾病 (牛皮,亚托邦性皮肤炎,性炎,大发) 显著影响生活质量,并带来社会经济成本.
- 拉丁美洲面临着独特的挑战,包括卫生系统的分散,社会经济不平等以及这些疾病的流行病学数据有限.
研究的目的:
- 审查拉丁美洲的牛皮 (PsO),亚托皮性皮肤炎 (AD),补充性海炎 (HS) 和空白脱发 (AA) 的流行病学,意识和治疗格局.
- 突出区域指导方针,现实世界的证据,以及在拉丁美洲背景下管理这些炎症性皮肤疾病的未满足需求.
主要方法:
- 采用了叙事审查方法.
- 数据是从同行评审的出版物,国家/区域指南,注册表分析和现实研究到2025年的数据中合成的.
主要成果:
- 流行率估计:PSO (0.5-2%),AD (2-3%的成年人),HS (0.3-0.5%),AA (1-2%的终身风险).
- 意识低,诊断延迟/治疗不足的情况普遍存在.
- 国家指导方针与国际标准保持一致,但适应当地限制;由于成本,保险和监管障碍,生物/向治疗的准入不公平.
- 现实数据证实了治疗效益,但强调了持续的差异和数据缺口.
结论:
- 在拉丁美洲,尽管有治疗进展,但炎症性皮肤疾病的获取和结果仍然存在重大不平等.
- 协调的区域注册,协调的临床指南和政策改革对于公平的皮肤病护理至关重要.
- 加快药品批准和补偿流程对于解决未满足需求至关重要.
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