仍然是相同的调节:与抗生素相关的不良事件率没有变化,支持对门诊抗菌药物管理的需求
Ganga Moorthy1,2, Matthew P Kronman3,4
1Department of Pediatrics, Duke School of Medicine; Durham, North Carolina.
Journal of the Pediatric Infectious Diseases Society
|December 30, 2025
概括
儿童抗生素相关的不良事件从2019年至2023年总体每年下降. 然而,2023年的事件恢复到了历史水平,突出显示了持续抗菌药物管理的必要性.
科学领域:
- 儿科健康 儿科健康
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 与抗生素相关的不良事件 (AAEs) 是儿童群体的一个重大问题.
- 2019-2023年期间包括COVID-19大流行,这是医疗保健模式的主要破坏者.
研究的目的:
- 分析2019年至2023年儿科AAE的趋势.
- 评估COVID-19大流行对这些趋势的影响.
- 评估对门诊抗微生物药物管理的持续需求.
主要方法:
- 对2019-2023年儿科AAE数据的回顾性分析.
- 年度AAE率的统计比较.
- 对AAE发生的流行病相关影响的评估.
主要成果:
- 在研究期间,观察到儿科AAE的整体年平均数量下降.
- 然而,仅2023年的AAE就与大流行前的历史数字相当.
- COVID-19大流行影响了儿科AAE中观察到的趋势.
结论:
- 尽管总体下降了,但2023年的儿科AAE表明恢复到基线水平.
- 持续的门诊抗菌药物管理计划对于管理儿科AAE至关重要.
- 流行病时代的变化需要对抗微生物药物的使用保持持续警.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Antibiotic Selection
59.3K
Overview
59.3K
Acute Pyelonephritis II: Diagnostic Studies and Management
267
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
267
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
224
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
224
Development of Antibiotic Resistance
1.1K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.1K
Urine Studies II: Urine Culture and Sensitivity Test
716
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
716


