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3替代的triazolone-benzoate杂交物:合成,酶抑制,抗癌活性和ADMET通过分子对接和动力学研究的ADMET评估

Murat Beytur1, Elif Tarmaşır1, Ercan Oguz2

  • 1Department of Chemistry, Faculty of Science and Letters, Kafkas University, Kars, Türkiye.

Drug development research
|December 30, 2025
PubMed
概括

合成了八种新的三龙化合物,并对它们对人类卵巢癌细胞的抗癌特性进行了评估. 这些化合物还对乙胆酶 (AChE) 和谷氨S转移酶 (GST) 酶表现出显著的抑制作用,具有有利的药物样性特征.

关键词:
一,二,四-三醇的使用.在OVCAR-3中使用OVCAR.这里是船只基地.酶抑制抑制酶的抑制.分子动力学分子动力学

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