口服药物治疗激动在安全网急诊室的治疗
Jon B Cole1,2, Kowsar M Hurreh1, Leyla A Taghizadeh1
1Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, Minnesota.
紧急服务部门成功地增加了口服药物用于激动,特别是因中毒而使用的药物. 口服和肌肉内路线显示了类似的镇静时间和安全性,支持口服第一线治疗指南建议.
科学领域:
- 紧急医疗 紧急医疗
- 药理学 药理学是指药理学的学科.
- 提高质量 提高质量
背景情况:
- 最佳实践指南主张口服药物用于应急部门 (ED) 的激动.
- 关于ED患者口服药物的使用,特别是对药物和酒精中毒的研究有限.
- 肌肉内药物是研究ED中兴奋治疗的标准.
研究的目的:
- 评估ED中治疗兴奋的口服药物的实施情况.
- 增加口服药物的利用,而不是肌肉内途的激发.
- 评估口服与肌肉内激发药物的有效性和安全性.
主要方法:
- 一项质量改进研究,比较城市创伤中心ED的干预前后期 (2018-2024年).
- 在12个月的实施期间 (2020-2021) 在专门的中毒护理领域进行前性观察.
- 教育和实时反被用来鼓励ED工作人员使用口服药物 (如奥兰扎,洛拉泽).
主要成果:
- 接受首次口服镇静药物的患者比例在干预后从7.2%显著增加到31.4%.
- 在实施期间,53.5%的符合条件的患者被提供了口服药物,70.8%接受了它.
- 在足够的镇静时间,额外的救援药物使用率或口服和肌肉内途之间的不良药物反应之间没有观察到显著的差异.
结论:
- 紧急医生成功地采用了口服药物来治疗激动,特别是在中毒的情况下.
- 口服和肌肉内注射药物在激发管理方面表现出可比的疗效和安全性.
- 这些发现支持当前的指导方针,建议口服药物作为ED动荡的第一线治疗.
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