跨性别者和非双性人之间的亲密伴侣暴力和艾滋病毒预防:前性混合方法队列研究的协议
Erik D Storholm1,2,3, Keith J Horvath4, Adedotun Ogunbajo2
1School of Public Health, San Diego State University, San Diego, CA, United States.
JMIR research protocols
|December 30, 2025
概括
经历亲密伴侣暴力 (IPV) 的跨性别和非二进制个体面临更高的艾滋病毒风险. 这项研究考察了IPV如何影响艾滋病毒预防行为,如测试和PrEP在这个人群中使用.
科学领域:
- 公共卫生 公共卫生
- 社会医学科学 社会医学科学
- 流行病学 流行病学
背景情况:
- 跨性别和非二进制 (TNB) 个体经历亲密伴侣暴力 (IPV) 的几率是 cisgender 人群的两倍.
- IPV与TNB人群中艾滋病毒风险和脆弱性增加有关,但其对预防行为的影响未得到充分研究.
- IPV的经验复杂,与系统性边缘化交叉,需要对特定机制进行研究.
研究的目的:
- 在TNB个体中调查IPV (事和受害) 与艾滋病毒相关结果之间的风险和保护途径.
- 了解IPV如何影响无避孕套的性行为,性传播感染和暴露前预防 (PrEP) 的吸收,坚持和持续性.
- 为受IPV影响的TNB社区提供量身定制的HIV预防策略.
主要方法:
- 一个前性的,连续的混合方法队列研究,涉及两个阶段.
- 第一个阶段:对32名TNB个人进行定性访谈,这些人最近有IPV经验,还有10名关键信息人.
- 第二阶段:为期24个月的基于网络的纵向队列研究,对600名HIV阴性,与TNB合作的个人进行,包括调查和在家收集HIV/STI测试和PREP遵守的生物样本.
主要成果:
- 第一阶段的定性访谈从2023年10月到2024年10月进行.
- 快速定性分析于2025年1月完成,以告知第二阶段测量选择.
- 第二阶段招生于2025年2月开始,预计将持续到2025年12月.
结论:
- 该研究将提供关键的见解IPV和艾滋病毒风险/预防之间的关系在TNB个人.
- 结果将指导性别肯定,创伤反应和文化基础干预的发展.
- 这项研究旨在改进针对TNB社区独特需求的HIV预防.
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