无对比CT食道静脉通过临床先前增强的多器官分析进行分级
Xiaoming Zhang1, Chunli Li2, Jiacheng Hao3
1Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, 110004, China; Alibaba Group, DAMO Academy; Faculty of Science and Engineering, Sorbonne University, Paris, 75005, France; Hupan Lab, Hangzhou, 310023, China.
Medical image analysis
|December 30, 2025
概括
一个新的AI工具,多器官凝聚网络++ (MOON++),分析CT扫描以非侵入性检测食道静脉 (EV) 和其严重程度,为肝硬化患者提供了内镜的有希望的替代方案.
科学领域:
- 放射学和医学成像学 医学成像学
- 医疗保健中的人工智能
- 胃肠病学和肝病学
背景情况:
- 食道静脉 (EV) 是肝硬化患者的门高血压的严重并发症,携带高出血风险.
- 目前的诊断依赖于侵入性内镜检查,这凸显了对非侵入性替代品的需求.
- 临床观察将肝脏疾病的严重程度与器官体积关系联系起来,建议采用多式成像方法.
研究的目的:
- 引入多器官凝聚网络++ (MOON++),一种新的多式人工智能框架,用于使用非对比计算断层扫描 (NCCT) 评估食道静脉 (EV).
- 评估MOON++在与传统单器官分析方法相比,对EV严重性进行分类的表现.
- 通过与经验丰富的放射科医生进行读者研究来验证MOON++的临床实用性.
主要方法:
- 开发了MOON++,一个多式联网深度学习框架,集成来自NCCT扫描的食道,肝脏和脏的成像数据.
- 训练并验证了MOON++在1631名内镜证实EV患者的大队伍中,分为四个严重程度.
- 将MOON++性能与单个器官分析方法进行比较,使用曲线下的面积 (AUC) 度量来进行EV分类.
主要成果:
- 在分类严重的EV (G3与
- 在区分中度至重度EV (≥G2与
- 读者研究证实了MOON++在协助放射科医生进行EV评估方面的有效性.
- 在区分中度至重度EV (≥G2与
结论:
- 通过分析NCCT扫描中的多器官关系,MOON++为食道静脉评估提供了一个有前途的非侵入性诊断工具.
- 这种人工智能框架有可能改善肝硬化患者门高血压并发症的管理.
- MOON++在利用多式成像和人工智能用于非侵入性疾病诊断方面取得了重大进展.
相关概念视频
Esophageal Varices-II: Clinical Features and Management
337
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
337
Esophageal Varices-I: Introduction
1.1K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
1.1K
Esophageal Strictures-II: Clinical Features and Management
384
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
384
Imaging Studies for Cardiovascular System V: CT
252
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
252
Barrett Esophagus-II: Clinical Manifestations and Management
735
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
735
Esophageal Perforation-II: Clinical Manifestations and Management
460
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
460


