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Updated: Jan 7, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
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肝纤维化和肝癌是肝纤维化的原因之一

Aina Anton1, Scott Laurence Friedman2, Bruno Cogliati3,2

  • 1Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas, Madrid, Spain.

Seminars in liver disease
|December 30, 2025
PubMed
概括

肝纤维化,不仅仅是肝硬化,可以启动肝癌 (肝细胞癌,HCC). 纤维化重塑肝脏的微环境,促进炎症和免疫抑制,甚至在肝硬化之前推动癌症的发展.

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