植物中芳香类生物合成的基因组机制
Menglan Wang1, Wenjie Xu1, Qizhen Chen1
1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Journal of advanced research
|December 30, 2025
概括
植物基因组揭示了不同物种如何产生相同的芳香化合物. 分析合成酶 (TPSs) 提供了对它们的演变和农业和工业工程的洞察.
科学领域:
- 植物生物化学和基因组学
- 代谢学和进化生物学
背景情况:
- 芳香特酸是重要的植物化合物,具有重要的生理和商业价值.
- 完全相同的芳香特尔佩诺酸可以由亲密和远距离相关的植物物种合成.
- 基因组测序的进步使得研究这种现象的基因组基础成为可能.
研究的目的:
- 突出整个基因组数据作为一种研究植物中芳香类生物合成机制的策略.
- 为合成酶 (TPSs) 的起源,进化和工程提供新的视角.
- 为植物育种带来好处,提高工业生产的适用性.
主要方法:
- 在34个植物基因组中对TPS进行全基因组识别和植物遗传学分析.
- 对TPS的功能和结构特征,重点关注活跃腔结构.
- 进行比较基因组分析以了解TPS基因起源模式.
主要成果:
- 在34个植物基因组中确定了1643个TPS,分为七个子家族.
- 在不同物种中具有相同功能的TPS显示出较低的序列相似性,但保留了活性腔.
- 相关物种中功能上不同的TPS表现出基因组分类,但不同的活性腔结构.
- 确定了三种TPS基因起源模式:并联重复,分散重复和没有重复的基因.
结论:
- 全基因组数据是研究芳香特类生物合成的强有力的方法.
- 了解TPS的演变和功能是植物育种和工业应用的关键.
- 基因组机制提供了关于芳香特类合成的融合演变的见解.
相关概念视频
Cell Signaling in Plants
6.1K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
6.1K
Amino Acid Biosynthetic Pathways
989
Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which...
989
C4 Pathway and CAM
48.5K
Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
C4 Pathway
The C4 pathway is used by plants such as...
48.5K
Plant Hormones
27.1K
Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
27.1K
Aromatic Compounds: Overview
13.3K
In general, the term ‘aromatic’ indicates a pleasant smell or fragrance from fresh flowers, freshly prepared coffee, etc. In the early history of organic chemistry, many benzene derivatives were isolated from the pleasant odor oils of the plants. For example, vanillin was isolated from the oil of vanilla, methyl salicylate from the oil of wintergreen, and cinnamaldehyde from the oil of cinnamon. They all had a pleasant odor; hence the name aromatic was given.
In 1825, Faraday isolated...
In 1825, Faraday isolated...
13.3K
Morphogenesis
30.1K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
30.1K


