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Updated: Jan 7, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
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慢性淋巴细胞白血病B细胞受体的缺陷细胞自主信号和抗原多活性 刻板印象的子集1

Paolo G Cocomazzi1, Anastasia Iatrou2, Claudia Minici1

  • 1Biocrystallography Unit, Department of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, 20132, Milano, Italy.

Nature communications
|December 30, 2025
PubMed
概括

慢性淋巴细胞白血病 (CLL) B细胞受体 (BCRs) 来自子组1并没有自主发出信号. 这表明其他机制驱动了CLL的进展,挑战了以前关于这种侵略性白血病中BCR信号传递的假设.

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