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Updated: May 13, 2026

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通过针对Shroom3-Rock相互作用来设计用于CKD风险等位基因的精密治疗方法

Anand Reghuvaran1, Ashwani Kumar1, Qisheng Lin2

  • 1Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.

Nature communications
|December 30, 2025
PubMed
概括

room3变种影响纤维化和白蛋白尿. 研究人员通过Rho-酶激活确定了一种特定的Shroom3动机,通过Rho-酶激活驱动纤维化,从而导致病的新治疗策略.

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