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在急性感染2年后,COVID-19后症状,主观工作能力和病假-基于人口的长期COVID研究结果
Stefanie Braig1, Raphael S Peter2, Alexandra Nieters3
1Institute of Epidemiology and Medical Biometry, Ulm University, Helmholtzstraße 22, 89081, Ulm, Germany. stefanie.braig@uni-ulm.de.
BMC public health
|December 30, 2025
概括
后COVID综合征显著影响工作能力和病假,疲劳和神经认知问题等症状持续长期. 诸如年龄和心理健康等修饰因素会影响康复和恢复工作.
科学领域:
- 职业健康 职业健康 职业健康
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 后COVID综合征 (PCS) 与工作能力降低,病假增加和工作回归延迟有关.
- 复杂性源于多种PCS症状和多方面的工作能力因素.
研究的目的:
- 调查SARS-CoV-2感染后工作能力和病假的长期演变.
- 确定影响后COVID时期劳动能力和病假的因素.
主要方法:
- 在西南德国进行基于人口的纵向研究 (n=5422,年龄在18-65岁之间).
- 评估工作能力 (mWAI1),与任务相关的工作能力 (mWAI2) 和病假在SARS-CoV-2感染后6-24个月 (PCR确认).
- 使用描述性分析和调整的线性回归模型.
主要成果:
- 1.1%的人在感染后的24个月内仍在持续的病假中.
- 持续/新的症状 (疲劳,神经认知,心理健康) 阻碍了恢复感染前的工作能力 (mWAI1) 和减少与任务相关的能力 (mWAI2).
- 年龄,工作任务和并发性精神疾病改变了风险因素的关联;在体力劳动的个人中,进一步的感染加剧了mWAI2.
结论:
- 已确认的已知风险因素对于COVID后的工作能力和病假.
- 突出了效果修饰物的显著影响,如工作任务和并发性精神障碍.
- 确定了与SARS-CoV-2感染后长期病假相关的关键变量.
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