核心成果集用于报告来自国际瘤结果小组共识研究的胆固醇瘤手术结果
Adrian L James1,2, Edward A Sykes2,3, Elliott Kozin4
1Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, Toronto, Canada.
概括
现在可以通过新的核心结果集 (COS) 来进行胆固醇瘤手术的标准化报告. 该框架旨在提高胆固醇瘤管理中的外科决策的证据质量.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术结果研究研究.
- 基于证据的医学基于证据的医学.
背景情况:
- 发表的关于胆固醇瘤手术的证据有限.
- 不一致的结果报告,包括区分残留与复发性胆固醇瘤和听力测量标准,阻碍了决策.
- 系统性审查强调需要提高胆固醇瘤管理数据质量.
研究的目的:
- 建立基于共识的核心结果集 (COS) 来报告胆固醇瘤手术的结果.
- 为胆固醇瘤手术研究制定标准化出版指南.
- 提高耳外科手术中证据的质量和可比性.
主要方法:
- 国际瘤学结果小组 (IOOG) 使用了COS-STAD和COS-STAR指南.
- 一个系统的文献审查和利益相关者商告知了结果的选择.
- 一个涉及IOOG成员和耳科学会董事会的德尔菲过程通过调查和电子邮件完善了COS,达到≥85%的共识.
主要成果:
- 报告标准的原则要求区分残留和复发性胆固醇瘤,使用5年生存率分析,详细说明残留检测技术,并应用听力测量标准.
- 建议的标准包括报告胆固醇瘤严重程度和外科术术名称.
- 患者报告的结果指标 (PROMs) 已被承认,但由于反应不足,尚未完全定义.
结论:
- 已经制定了一个基于共识的核心结果集 (COS) 用于在胆固醇瘤手术中进行标准化报告.
- 预计采用该COS作为出版标准将提高指导外科护理的证据质量.
- 这一框架将促进更好的临床决策和研究可比性.
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