立陶宛成年人心血管--代谢 (CKM) 综合征的患病率:使用电子健康记录进行全国实践研究的见解
Gediminas Urbonas1, Indrė Čeponienė2, Inga Arūnė Bumblytė3
1Department of Family Medicine, Medical Academy, Lithuanian University of Health Sciences, Eiveniu 2, 50161 Kaunas, Lithuania.
Medicina (Kaunas, Lithuania)
|December 31, 2025
概括
超过40岁的立陶宛成年人中有三分之一患有心血管--代谢 (CKM) 综合征. 对CKM综合征的生物标志物测试的使用不足表明错过了早期检测机会,需要综合护理.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 心血管--代谢 (CKM) 综合征将代谢问题,慢性病 (CKD) 和心血管疾病 (CVD) 联系在一起.
- 关于CKM综合征患病率的人口数据很少,特别是在欧洲,很少.
- 立陶宛缺乏关于CKM综合征和生物标志物利用的全面数据.
研究的目的:
- 为了确定CKM综合征在年龄≥40岁的立陶宛成年人中的患病率.
- 评估脏 (eGFR,ACR) 和心脏 (NT-proBNP) 生物标志物在管理CKM综合征中的利用.
- 确定早期检测和干预CKM综合征的机会.
主要方法:
- 对923329名立陶宛成年人 (≥40岁) 的健康记录进行分析.
- 鉴定CKM相关的疾病 (肥胖,糖尿病,CKD) 和心血管结果 (动脉样性心血管疾病,心力衰竭,心房动).
- 对CKM阶段 (0, 1-3, 4) 的分类和对eGFR,ACR和NT-proBNP测试率的评估.
主要成果:
- 34.8%的成年人患有4期CKM综合征;23.4%患有1-3期.
- 肥胖 (21.2%) 和2型糖尿病 (17.2%) 是最常见的CKM疾病.
- 心力衰竭 (25.4%) 和心房动 (14.0%) 是常见的心血管疾病结局;生物标志物测试率低 (eGFR 53.5%,ACR 9.0%,NT-proBNP 4.9%).
结论:
- 相当一部分立陶宛成年人 (≥40岁) 患有CKM综合征.
- 生物标志物测试的不足利用代表了早期CKM综合征检测和管理的错失机会.
- 综合护理和更广泛的生物标志物实施对于减轻CKM综合征进展和心血管风险至关重要.
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