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玻璃眼中微脉冲激光形整形:临床队列中的有效性和安全性

Flaviu Ionut Bodea¹, Cristina Ariadna Nicula¹, Delia Mirela Tit^1,2

¹Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.

Medicina (Kaunas, Lithuania)

|December 31, 2025

概括

微脉冲激光膜整形 (MLT) 有效降低了青光眼患者的眼内压力 (IOP),证明了安全和临床相关的降低. 视觉功能与最小的不良事件保持稳定,这表明MLT是可行的IOP管理选项.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
激光疗法是一种激光疗法.

背景情况:

玻璃眼是不可逆转的失明的主要原因.
降低眼内压力 (IOP) 是唯一已确定的方法来减缓青光眼的进展.
评估微脉冲激光膜整形术 (MLT) 治疗青光眼和眼睛高血压的疗效和安全性至关重要.

研究的目的:

评估MLT在控制IOP方面的临床有效性.
评估MLT对视觉功能的影响,包括最佳校正视敏度 (BCVA) 和折射.
记录与MLT治疗相关的任何不良事件.

主要方法:

一个纵向的,现实世界的队列研究,涉及80名患者 (132只眼睛) 用MLT治疗.
在360度范围内进行MLT,根据临床因素的变化.
使用戈德曼和非接触性度计测量内压力;还记录了BCVA,折射和安全事件.

主要成果:

三个月后,平均内血压从18.15 ± 5.02 降至15.57 ± 3.78 mmHg (p < 0.001).
实现目标IOP范围 (≤18 mmHg和≤21 mmHg) 的眼睛比例显著增加.
稳定的BCVA和折射;没有观察到重大并发症或显著的IOP峰值.

结论:

通过MLT,在开角玻璃眼和眼睛高血压患者中,显示出安全且具有临床意义的IOP降低.
在MLT后观察到稳定的视觉功能和最小的不良影响.
MLT为IOP管理提供了一个有希望的选择,尽管需要进一步的受控研究来确认因果关系.

关键词:

眼内压力眼内压力激光治疗是一种激光疗法.微脉冲激光形整形手术是微脉冲激光形手术.不侵入性治疗是一种非侵入性治疗.视角开放的玻璃眼 (Glaucoma) 是一种

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