肺功能和COVID-19后儿童的相关预后因素:一项回顾性队列研究
Mega Septiana1, Nastiti Kaswandani1, Irene Yuniar1
1Department of Child Health, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Medicina (Kaunas, Lithuania)
|December 31, 2025
概括
近一半的儿童经历COVID-19后的肺功能受损,特别是那些持续症状或严重疾病的儿童. 营养不良的儿童在COVID-19后也面临更高的长期呼吸系统问题的风险.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 儿童COVID-19幸存者的呼吸系统后果报告不足.
- 了解长期的肺功能对于这一群体至关重要.
研究的目的:
- 为了确定COVID-19后儿童呼吸功能受损的患病率.
- 确定影响儿童COVID-19幸存者的长期呼吸结果的预后因素.
主要方法:
- 对100名确诊COVID-19的儿科患者 (5-18岁) 进行了回顾性队列研究.
- 通过螺旋计测量评估呼吸功能.
- 分析的预后因素包括COVID-19的严重程度,并发症和持续症状.
主要成果:
- 47%的儿童表现出肺功能受损,主要是限制性模式.
- 持续的症状与异常的螺旋计显著相关 (RR 1.99).
- 营养不良和中度至危急的COVID-19严重程度与较差的呼吸功能有关 (aOR分别为5.64和5.18).
结论:
- 在COVID-19后的儿童中,肺功能障碍的显著流行存在.
- 持续的症状,营养不良和严重的COVID-19是不良呼吸系统结果的关键预测因素.
- 建议进行进一步的前性研究,以阐明因果途径.
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