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跨关节认知融合,系统和组合活检用于前列腺癌检测的比较分析
Mihai Alexandru Radu1, Sorin Cecil Mirea2, Andrei Drocaș1
1Department of Urology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Medicina (Kaunas, Lithuania)
|December 31, 2025
概括
认知融合 (CF) 活检与系统活检 (SB) 相比,改善了前列腺癌检测和风险评估. 结合这两种方法为PI-RADS ≥3病变提供了最高的诊断性能.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 多参数MRI (mpMRI) 增强了前列腺癌 (PCa) 的检测.
- 对于PCa,认知融合 (CF) 活检与系统活检 (SB) 的比较诊断价值仍在调查中.
研究的目的:
- 预期评估SB,CF及其组合在前列腺成像和报告数据系统 (PI-RADS) ≥3病变的患者的诊断性能.
- 与SB相比,评估CF对风险分层的影响.
主要方法:
- 282名PI-RADS ≥3病变患者接受了mpMRI,随后进行了SB和CF活检.
- 在SB和CF之间,癌症检测率和国际泌尿病学学会 (ISUP) 评级进行了比较.
主要成果:
- 综合方法检测到所有154个PCa病例,单独超过SB (112种癌症) 和CF (135种癌症).
- CF确定了42种由SB错过的癌症,并改善了风险分层,升级了38名患者.
- 在41例病例中,SB低估了疾病的严重程度.
结论:
- CF活检在检测临床显著的PCa和精制风险分层方面表现优于SB.
- 结合的SB和CF方法提供了最高的诊断产量,支持其整合到前列腺癌评估协议.
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