坚果消费与抑郁症状风险之间的关联:观察性研究的元分析
Sohyun Kim1, Hyogyeong Lee1, Qiao-Yi Chen1
1Department of Food Science and Biotechnology, Dongguk University, SangYeong Building Room 543, Siksa-dong, Goyang-si 10326, Gyeonggi-do, Republic of Korea.
Nutrients
|December 31, 2025
概括
经常食用坚果,特别是每周三次或更多次,与抑郁症状的风险降低有关. 这一元分析阐明了饮食中坚果摄入量与精神健康之间的关联.
科学领域:
- 营养精神病学 营养精神病学
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 包括坚果在内的饮食因素越来越多地被认为对心理健康的潜在影响.
- 现有的关于坚果消费和抑郁症状的研究显示出不一致的结果.
- 澄清这种关系对于公共卫生建议至关重要.
研究的目的:
- 对观察性研究进行全面的元分析.
- 调查坚果消费与抑郁症状风险之间的关联.
- 为了更清楚地了解这种饮食与心理健康的联系.
主要方法:
- 在PubMed和Embase数据库中进行系统的文献搜索,截至2025年9月.
- 包括七项观察性研究,共有70,136名参与者.
- 使用DerSimonian-Laird随机效应模型进行元分析,以估计总结相对风险 (SRR) 和95%置信区间 (CI).
主要成果:
- 总体较高的坚果消费与较低的抑郁症状风险显著相关 (SRRs = 0.75,95%CI,0.67-0.85).
- 摄入坚果≥3次/周显示与抑郁症状有显著的反向关系 (SRRs = 0.75,95%CI = 0.63-0.89).
- 对于每周1至3次的坚果消费没有发现显著的关联 (SRRs = 0.93,95%CI = 0.69-1.24).
结论:
- 较高的坚果消费,特别是每周≥3份,与抑郁症状的风险降低有关.
- 这些发现支持定期摄入坚果对抗抑郁症的保护作用.
- 建议进行进一步的研究,包括随机对照试验,以阐明潜在机制.
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