在多发性硬化症患者的功能状态的评估,基于他们的饮食的炎症潜力
Sofía Fernández-Godino1, Irene Cabrera-Martos1, Alejandro Heredia-Ciuró1
1Department of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Nutrients
|December 31, 2025
概括
促炎症饮食与多发性硬化症 (MS) 患者的症状恶化有关. 抗炎饮食可以改善MS患者的功能和生活质量.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- 多发性硬化症 (MS) 是一种慢性,炎症性中枢神经系统疾病,影响年轻人,导致渐进的残疾和生活质量的降低.
- 饮食中的炎症潜力是影响多发性硬化症进展和症状严重性的新兴因素.
- 本研究调查了MS患者的饮食模式和功能结果之间的关系.
研究的目的:
- 测试一种促炎性饮食与与抗炎性饮食相比,MS患者的功能结果较差的假设.
- 探索饮食炎症潜在对MS患者症状负担和生活质量的影响.
主要方法:
- 一项观察性初步研究包括19名多发性硬化患者.
- 使用饮食炎症指数 (DII) 评估了饮食炎症潜力.
- 使用MS的功能评估 (FAMS) 尺度来测量功能状态.
主要成果:
- 与抗炎症饮食 (n=9; 14.44 ± 7.05, p=0.044) 患者相比,支持炎症饮食的患者 (n=10) 报告了较高的症状负担 (FAMS 症状得分为 20.70 ± 5.48).
- 支持炎症的组体验到更大的疲劳,肌肉骨和胃肠道的投诉.
- 抗炎症组报告症状较少,摄入纤维,和维生素B6等营养素较高.
结论:
- 针对炎症的饮食干预可以提高MS患者的功能和生活质量.
- 初步证据表明,饮食和MS症状严重程度之间存在联系.
- 由于样本规模有限,需要进行更大规模的多中心纵向研究来证实这些发现.
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