食补充剂干预和改善睡眠质量:系统性审查和元分析
Meijuan Mei1,2, Qiya Zhou1, Wenting Gu1,2
1College of Food Science, South China Agricultural University, Guangzhou 510642, China.
Nutrients
|December 31, 2025
概括
食补充剂,如托,维生素D,欧米茄-3,和抗氧化剂显著改善睡眠质量. 这些干预措施可以减少睡眠延迟,并在入睡后醒来,同时提高睡眠效率和总睡眠时间.
科学领域:
- 营养科学 营养科学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠健康对整体健康至关重要,睡眠不足是一个日益严重的公共卫生问题.
- 包括营养补充在内的饮食干预措施被认为是提高睡眠质量的有效策略.
研究的目的:
- 系统地评估饮食补充剂干预措施对睡眠质量的有效性,在有睡眠障碍和没有睡眠障碍的人群中.
- 综合来自随机对照试验对营养补充剂对各种睡眠指标的影响的证据.
主要方法:
- 在多个科学数据库 (PubMed, Web of Science, CNKI, ScienceDirect, Wiley, CVIP) 进行了全面的文献搜索.
- 包括的研究是随机对照试验 (RCT),评估改善睡眠的食补充剂干预措施.
- 分析的关键睡眠指标包括匹兹堡睡眠质量指数 (PSQI),睡眠效率 (SE),睡眠延迟 (SL),总睡眠时间 (TST),入睡后醒来 (WASO) 和入睡后醒来 (NASO).
- 使用Review Manager 5.3和Stata 17.0.0进行了元分析.
主要成果:
- 分析包括28个RCT,表明饮食干预显著改善了睡眠结果.
- 饮食干预导致PSQI得分的降低 (MD: -0.70) 和缩短SL (SMD: -0.24) 和WASO (SMD: -0.30).
- 在增加的SE (+2.58分钟) 和延长的TST (SMD: +0.23) 中也观察到改善,NASO的边际减少 (MD: -1.57).
结论:
- 特定的营养素,如托,维生素D,欧米茄-3脂肪酸,和抗氧化剂,显示出提高睡眠质量的潜力.
- 这些补充剂似乎通过减少睡眠延迟和睡眠开始后醒来来改善睡眠,同时增加睡眠效率和总睡眠时间.
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