对过敏性鼻炎的草药吸入疗法:系统性审查和元分析
Sang-Song Shim1, Jung-Eun Kil2, Jiwon Park2,3
1Department of Internal Medicine, College of Korean Medicine, Wonkwang University, 460, Iksan-daero, Sin-dong, Iksan 54538, Republic of Korea.
Pharmaceuticals (Basel, Switzerland)
|December 31, 2025
概括
草药原子化吸入 (HMAI) 可能改善过敏性鼻炎 (AR) 患者的症状,特别是当与其他治疗一起使用时. 然而,由于目前的证据有限,需要进行更严格的研究.
科学领域:
- 综合医学是一个整体的医学.
- 药理学 药理学是指药理学的学科.
- 免疫学 免疫学 免疫学
背景情况:
- 过敏性鼻炎 (AR) 是一种影响生活质量的流行免疫性疾病.
- 目前针对AR的药物疗法往往无法充分控制症状.
- 草药原子化吸入 (HMAI) 是一种潜在的辅助或替代疗法.
研究的目的:
- 系统地审查和元分析HMAI对AR的临床疗效和安全性.
- 评估HMAI作为局部药物输送系统的有效性.
主要方法:
- 在2025年4月28日之前,对六个数据库进行了系统搜索.
- 包括随机对照试验 (RCT) 评估AR的HMAI.
- 随机效应元分析,Cochrane偏差风险2.0和GRADE被用于结果评估.
主要成果:
- 涉及1606名参与者的14个RCT符合标准.
- 与西方医学相比,HMAI显示出明显更高的总有效率 (RR = 1.20,95% CI 1.09-1.32).
- 当作为辅助疗法使用时,HMAI增强了症状缓解,尽管证据确定性是中等到非常低.
结论:
- HMAI可能为AR提供症状益处,特别是作为辅助疗法.
- 由于研究的可变性和偏差风险,研究结果应谨慎解释.
- 需要使用标准化方案进行高质量的安慰剂对照试验,以确认HMAI在AR治疗中的作用.
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