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Updated: Jan 7, 2026

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
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美国能源部和 PBBM驱动的配方开发一种延长释放的多尼佩齐尔片

Frederico Severino Martins1, Leonardo Luiz Borges2,3, Sivacharan Kollipara4

  • 1Institute of Technology and Research (ITP), Av. Murilo Dantas, 300, Aracaju 49010-390, Sergipe, Brazil.

Pharmaceuticals (Basel, Switzerland)
|December 31, 2025
PubMed
概括

整合实验设计 (DoE) 与生理基础生物制药建模 (PBBM) 简化了延长释放 (XR) 配方开发. 这种方法加快了生物同等药物产品的上市时间.

关键词:
盒子Behnken设计设计设计实验的设计.延长释放的配方可以使用.基于生理学的生物制药建模.虚拟的生物等价性

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