小麦作为天然抗菌化合物的仓库
Eva Scarcelli1, Domenico Iacopetta1, Jessica Ceramella1
1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.
Molecules (Basel, Switzerland)
|December 31, 2025
概括
小麦含有具有广泛抗微生物活性的天然化合物,为打击抗微生物耐药性 (AMR) 提供了可持续的替代方案. 研究强调了它对抗各种细菌和真菌的潜力.
科学领域:
- 农业科学 农业科学
- 生物化学 生化学
- 微生物学 微生物学
背景情况:
- 抗微生物药物耐药性 (AMR) 是一个日益增长的全球健康威胁,由抗微生物药物的滥用驱动.
- 天然抗微生物正在被探索作为替代治疗剂.
- 小麦是一种全球种植的作物,富含具有抗菌特性的生物活性化合物.
研究的目的:
- 审查小麦品种及其副产品的抗菌潜力.
- 确定小麦中负责抗菌作用的关键化合物.
- 评估小麦作为新型抗菌剂的可持续来源.
主要方法:
- 在谷歌学者和Scopus进行的文献搜索.
- 使用相关关键词对数据库进行选.
主要成果:
- 小麦含有多,,氧化,1,4-基和5-n-基.
- 这些植物化学物质在体外表现出广泛的活性,对抗阳性和阴性细菌和真菌.
- 确定了导致小麦抗菌作用的关键化合物.
结论:
- 小麦及其副产品是天然抗菌剂的有希望和可持续来源.
- 对小麦衍生化合物的进一步研究可能会导致针对AMR的新策略.
相关概念视频
Microorganisms in Agriculture and Food industry
1.2K
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
1.2K
Defense Mechanism Against Infection
9.1K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
9.1K
Antimicrobial Proteins
12.9K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.9K
Biological Methods for Microbial Control
758
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
758
Chemical Agents for Microbial Control
709
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
709
Surface Membrane Barriers
2.5K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
2.5K


