不同的益生菌输送方法在口腔候群病的比较有效性:系统性审查
Reihaneh Ashouritoustani1, Cláudia Pinho2, Ana Isabel Oliveira2
1ESS, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 400, 4200-072 Porto, Portugal.
Microorganisms
|December 31, 2025
概括
益生菌可以减少口腔Candida的殖民和候群病的症状. 不同的输送方法,如药片和囊,显示出作为补充性抗真菌疗法的希望.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 口腔健康 口腔健康
背景情况:
- 口腔角膜炎是一种主要由Candida albicans引起的真菌感染.
- 它不成比例地影响免疫力低下的个体,老年人和戴假牙的人.
- 益生菌通过调节免疫力和平衡口腔微生物群,具有潜在的抗真菌益处.
研究的目的:
- 系统地审查各种益生菌输送方法在治疗口腔候群病的有效性.
- 评估益生菌对坎迪达菌殖民和临床症状的影响.
主要方法:
- 根据PRISMA 2020指南进行了系统审查.
- 搜索包括来自Medline,Web of Science,ScienceDirect和ProQuest的人类临床研究.
- 测量结果是Candida负载,微生物群变化,症状改善和复发.
主要成果:
- 十项研究符合纳入标准,调查了像软,囊,酸奶和奶酪这样的输送方法.
- 大多数研究报告了Candida殖民地形成单位 (CFU) 的减少和Candida的流行率. 阿尔比卡和非阿尔比卡物种.
- 包括Lactobacillus和Bifidobacterium菌株在内的益生菌显示出有效性,一些研究指出改善了免疫学标志物和缓解症状,特别是在与抗真菌药物结合使用时.
结论:
- 益生菌有效地减少了香菌的殖民和口腔香病的症状.
- 它们显示出作为口腔候群病的辅助疗法的潜力.
- 进一步标准化,大规模试验是必要的,以优化益生菌的使用和交付方法.
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