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Pathophysiology of Heart Failure01:17

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
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Heart Failure I: Introduction01:27

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Heart Failure VII: Nursing Interventions01:30

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The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
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Heart Failure II: Pathophysiology01:29

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
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胃癌进展心力衰竭风险增加:全国性基于人口的队列研究

Seunghan Lee1, Mi Jin Oh1, Bokyung Kim1

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心力衰竭的风险随着胃癌的发展阶段而增加. 与局部疾病患者相比,患有远期胃癌的患者患心力衰竭需要住院治疗的风险几乎高出3倍.

关键词:
流行病学 流行病学胃癌 胃癌是指胃癌.心脏衰竭是因为心脏衰竭.风险因素 风险因素在 SEER 计划中,

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科学领域:

  • 在瘤学瘤学.
  • 心脏病学 心脏病学
  • 公共卫生 公共卫生

背景情况:

  • 由于治疗的进步,胃癌的生存率正在改善.
  • 在胃癌幸存者中,对与癌症无关的疾病,特别是心血管疾病的兴趣日益增加.
  • 胃癌阶段与心力衰竭风险之间的关系需要进一步研究.

研究的目的:

  • 为了研究胃癌患者心力衰竭的风险.
  • 根据胃癌的初始阶段分析心力衰竭风险.

主要方法:

  • 通过使用韩国癌症公共图书馆数据库进行了全国性,基于人口的回顾性队列研究.
  • 在2012年至2019年期间被诊断患有胃癌的患者被跟踪到2020年.
  • 胃癌的分期 (局部,区域,远程) 基于监测,流行病学和最终结果计划的标准.

主要成果:

  • 总共包括202,347名胃癌患者;7.9%的人患有心力衰竭.
  • 心力衰竭发病率在晚期胃癌阶段显著增加 (p<0.001).
  • 与局部阶段相比,心力衰竭的调整后危险比为1.52 (区域阶段) 和2.87 (远程阶段).

结论:

  • 需要住院治疗的心力衰竭的风险随着胃癌阶段的恶化而升级.
  • 密切监测心力衰竭对所有胃癌患者至关重要,包括年轻人和没有代谢风险因素的人.
  • 这些发现凸显了胃癌患者综合护理的重要性,解决了瘤和心血管健康问题.