胃癌进展心力衰竭风险增加:全国性基于人口的队列研究
Seunghan Lee1, Mi Jin Oh1, Bokyung Kim1
1Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Gut and liver
|December 31, 2025
概括
心力衰竭的风险随着胃癌的发展阶段而增加. 与局部疾病患者相比,患有远期胃癌的患者患心力衰竭需要住院治疗的风险几乎高出3倍.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 由于治疗的进步,胃癌的生存率正在改善.
- 在胃癌幸存者中,对与癌症无关的疾病,特别是心血管疾病的兴趣日益增加.
- 胃癌阶段与心力衰竭风险之间的关系需要进一步研究.
研究的目的:
- 为了研究胃癌患者心力衰竭的风险.
- 根据胃癌的初始阶段分析心力衰竭风险.
主要方法:
- 通过使用韩国癌症公共图书馆数据库进行了全国性,基于人口的回顾性队列研究.
- 在2012年至2019年期间被诊断患有胃癌的患者被跟踪到2020年.
- 胃癌的分期 (局部,区域,远程) 基于监测,流行病学和最终结果计划的标准.
主要成果:
- 总共包括202,347名胃癌患者;7.9%的人患有心力衰竭.
- 心力衰竭发病率在晚期胃癌阶段显著增加 (p<0.001).
- 与局部阶段相比,心力衰竭的调整后危险比为1.52 (区域阶段) 和2.87 (远程阶段).
结论:
- 需要住院治疗的心力衰竭的风险随着胃癌阶段的恶化而升级.
- 密切监测心力衰竭对所有胃癌患者至关重要,包括年轻人和没有代谢风险因素的人.
- 这些发现凸显了胃癌患者综合护理的重要性,解决了瘤和心血管健康问题.
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