慢性细菌和西卡喉炎:回顾性队列和系统性审查
Lauren A Howser1, Anuja H Shah1,2, Chandler J Curtis1
1Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.
The Annals of otology, rhinology, and laryngology
|December 31, 2025
概括
慢性细菌性喉炎 (CBL) 和细菌性喉炎 (SL) 存在诊断方面的挑战. 这项研究强调了对于这些重叠的喉疾病需要标准化指导方针的需要.
科学领域:
- 喉腔病理学 喉腔病理学
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 慢性细菌性喉炎 (CBL) 和病性喉炎 (SL) 在临床上相似,缺乏标准化的诊断或治疗方案.
- 由于症状和治疗反应重叠,区分CBL和SL是具有挑战性的.
研究的目的:
- 为了更好地定义慢性细菌性喉炎 (CBL) 和病性喉炎 (SL).
- 进行系统审查和回顾性队列分析,以澄清这些喉状况.
主要方法:
- 在PubMed,Scopus和CINAHL的系统文献审查中,遵守PRISMA指南.
- 在第三级喉科诊所对患者进行回顾性队列分析,收集有关症状,喉腔镜检查,治疗和结果的数据.
主要成果:
- 系统性审查确定了14项研究 (n=718),专注于CBL,没有发现SL研究.
- 在CBL患者中,失声症是最常见的症状 (85.3%),经常与使用质子抑制剂 (75.3%) 和吸烟 (57.8%) 相联系.
- 常见的病原体包括*金黄色葡萄球菌* (MSSA和MRSA) 和*克莱布西拉*. 治疗结果变化不定,有48.6%的患者得到解决,50.2%需要重新治疗. 追溯队列显示较低的分辨率 (9.5%),更高的再治疗 (38%) 和复发率 (32%),糖尿病与增加的再治疗需求有关.
结论:
- 由于它们的重叠性质,慢性细菌性喉炎 (CBL) 和病性喉炎 (SL) 存在重大诊断和治疗挑战.
- 目前诊断和管理的变化凸显了对标准化指导方针和有针对性的治疗策略的迫切需要.
- 改善治疗这些喉疾病的患者护理需要制定明确的诊断标准和基于证据的治疗计划.
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