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Updated: Jan 7, 2026

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

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由于DNASE2中DNASE2中的近位内拼接位变异,两名无关患者的I型干扰素介导自身炎症

Oskar Schnappauf, Hongying Wang, Qing Zhou

    Research square
    |December 31, 2025
    PubMed
    概括

    一种新的DNASE2拼接部位变异导致DNase II缺乏,导致I型干扰素介导的自身炎症. 这扩大了对罕见免疫疾病的理解,并支持JAK抑制作为治疗方法.

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