优化降脂协生菌:菌株选,协同联盟配方,益生菌调制和冷干燥工艺工程,以提高稳定性和有效性
Wenjing Zhu1,2, Qinggele Borjihan1,2, Yongfu Chen1,2
1Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China.
Food chemistry. Molecular sciences
|December 31, 2025
概括
这项研究开发了一种使用特定Lactobacillus菌株和乳糖的新型共生粉末,显示出显著的降脂活性. 优化的冷干燥过程确保其作为一种功能性食品成分的有效性,用于管理脂质代谢.
科学领域:
- 微生物学与食品科学 微生物学与食品科学
- 营养科学 营养科学
- 生物技术是生物技术.
背景情况:
- 脱脂症是全球主要的健康问题,需要创新的饮食干预措施.
- 协生菌,结合益生菌和益生菌,为调节脂质代谢提供了一个有希望的方法.
- 目前的研究正在寻求具有增强功能性质的有效共生配方.
研究的目的:
- 选和选择具有强大的体外降脂能力的乳酸细菌.
- 通过使用选定的菌株和乳糖,制定和优化共生成分.
- 优化冷干燥过程,以保持协生粉的活力和有效性.
主要方法:
- 对80种乳酸细菌菌株进行胆固醇和甘油三降解的查.
- 选择的菌株 (Lactobacillus pentosus 9-6和Enterococcus faecalis SMN3-2) 与乳糖共同培养.
- 使用Box-Behnken响应表面方法优化冷干燥参数.
- 评估活性的细菌数量和脂质降解效率的评估.
主要成果:
- 乳杆菌托9-6和菌 SMN3-2在体外显示高胆固醇和甘油三降解.
- 在2:1的比例下与乳糖共同培养提高了降解率,达到70.7% (胆固醇) 和58.8% (三糖).
- 经过优化的冷化,产生了4.63 × 10^9 CFU/g的粉末,降解效率为62.6% (胆固醇) 和53.8% (三甘油).
结论:
- 开发的共生系统通过一种特定的机制有效降低脂质,涉及乳酸菌株和乳糖.
- 冷干燥过程成功地保持了协生菌粉的功能功效.
- 这种协生性冷解粉是脂质调节食物和饮食干预措施的有价值的功能成分.
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