胸前大动脉感染的长期结果和发展趋势:一项为期25年的日本单中心研究
Katsuhiro Yamanaka1, Kenji Okada1, Daiki Kato1
1Division of Cardiovascular Surgery, The Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
JTCVS open
|December 31, 2025
概括
自2008年以来,胸前大动脉感染 (TAI) 的外科治疗改善了结果. 尽管死亡率高,但目前的策略为TAI患者提供了可接受的长期存活率.
科学领域:
- 心血管外科心血管外科
- 传染性疾病 传染性疾病
- 血管外科 血管外科
背景情况:
- 胸前动脉感染 (TAI) 是一种罕见但危及生命的疾病.
- TAI包括原生主动脉感染,假体移植感染和主动食管/主动气管.
- 对TAI的手术管理带来了重大挑战和高死亡率.
研究的目的:
- 为了回顾25年的胸前大动脉感染手术经验.
- 评估外科手术策略对TAI管理的有效性.
- 为了识别TAI治疗的趋势和结果随着时间的推移.
主要方法:
- 从2000年1月到2024年9月,对106名TAI患者进行了回顾性研究.
- 分析初级终点 (医院死亡率) 和二级终点 (30天死亡率,存活率,不受感染).
- 2008年之前和之后实施的手术策略之间的结果比较.
主要成果:
- 这项研究包括106名患有TAI的患者,包括囊和移植感染.
- 医院死亡率为16.0%,30天死亡率为3.7%.
- 自2008年以来的手术管理显示出明显改善的结果,10年整体存活率为55.4%.
结论:
- 自2008年以来实施的TAI手术策略已经改善了患者的治疗结果.
- 尽管死亡率高,但TAI的长期结果被认为是可以接受的.
- 持续改进手术技术对于管理复杂的TAI病例至关重要.
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