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相关概念视频

Organization of the Brain01:30

Organization of the Brain

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The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
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Anatomy of the Brain: Major Regions01:20

Anatomy of the Brain: Major Regions

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The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
9.5K
Brain Imaging01:14

Brain Imaging

629
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
629
Cerebrum: Anatomical Overview II01:11

Cerebrum: Anatomical Overview II

4.2K
Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
4.2K
Cerebrum: Anatomical Overview I01:26

Cerebrum: Anatomical Overview I

4.6K
The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...
4.6K
Anatomy of the Brain: Ventricles01:18

Anatomy of the Brain: Ventricles

7.8K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
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相关实验视频

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Serial Two-Photon Tomography of the Whole Marmoset Brain for Neuroanatomical Analyses
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Serial Two-Photon Tomography of the Whole Marmoset Brain for Neuroanatomical Analyses

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一个互动的知识大脑图谱.

Leon Stefanovski, Konstantin Bülau, Leon Martin

    bioRxiv : the preprint server for biology
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    PubMed
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    此摘要是机器生成的。

    我们开发了语义的虚拟大脑适配器 (TVBase),这是一个将数百万篇文章的生物医学知识投射到3D大脑模型上的平台. 该工具通过将文献数据与大脑解剖学联系起来,有助于神经成像研究和个性化医学.

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    Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
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    Modeling the Functional Network for Spatial Navigation in the Human Brain
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    Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
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    科学领域:

    • 神经科学是一个神经科学.
    • 计算生物学 计算生物学
    • 生物信息学是一种生物信息学.

    背景情况:

    • 生物医学知识正在迅速扩大,为人类的理解带来了挑战.
    • 现有的文献挖掘工具很难将语义方法与神经成像标准整合起来.
    • 这种差距阻碍了在脑研究中充分利用生物医学数据.

    研究的目的:

    • 开发一个语义元分析平台,TVBase,将生物医学知识投射到标准化的3D大脑上.
    • 弥合基于文献的生物医学信息和神经成像数据之间的差距.
    • 支持翻译和多尺度计算神经科学.

    主要方法:

    • 利用SCAIView平台从PubMed.com中提取生物医学实体及其大脑解剖学关联.
    • 使用基于的计算来确定概念和解剖学术语之间的关联强度.
    • 开发了一个转换矩阵,将800多个解剖学术语映射到标准大脑图谱的voxel坐标.

    主要成果:

    • 成功地将来自3600多万篇文章的生物医学知识投射到标准化的3D大脑上.
    • 启用特定区域的信息提取,将生物医学概念与大脑解剖学联系起来.
    • 创建了一个新的知识投影方法,支持计算神经科学.

    结论:

    • TVBase促进了无假设的神经成像模式的解释和假设生成.
    • 该平台通过整合文学数据与大脑结构来支持个性化医学的应用.
    • TVBase是一个开源的Python库,促进计算神经科学研究的可访问性.