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Updated: Jan 7, 2026

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在急性原肌细胞白血病中综合蛋白质和代谢分析:目前的状况和前景

Ting Liu1, Mengqi Qu2, Ning Wang1

  • 1Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116021, People's Republic of China.

International journal of general medicine
|December 31, 2025
PubMed
概括

蛋白质组学和代谢组学揭示了对急性肌肉细胞白血病 (APL) 病原和治疗反应的关键见解. 这些先进技术阐明了PML::RARα融合蛋白和免疫系统的作用,指导APL的精密医学.

关键词:
患有急性促细胞性白血病.免疫调节 免疫调节代谢产物的代谢产物代谢生物组的代谢生物组pml::rarα 聚变蛋白质是一种罕见的聚变蛋白.蛋白质组学 蛋白质组学治疗对治疗的反应反应.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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