同源骨移植的回顾性结果分析
Vikas Maheshwari1, Mohit Dhingra1, Divyansh Sharma1
1Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
South Asian journal of cancer
|December 31, 2025
概括
从手术残留物中新鲜冷的全移植在重建性手术中显示出有希望的结果. 骨移植的整合和承重能力在较低的感染率下实现,尤其是在增强后.
科学领域:
- 整形外科手术 整形外科手术
- 生物材料科学 生物材料科学
- 组织工程是组织工程.
背景情况:
- 骨库对于重建和瘤手术至关重要,为尸体和活体捐赠者提供异性骨.
- 来自活体捐赠者的手术残留物提供了基骨移植的宝贵来源.
研究的目的:
- 评估使用从活体捐赠者手术残留物中获得的新鲜冷全移植的重建手术的结果.
- 分析所有基骨移植受体的移植合并时间和感染率.
主要方法:
- 在2018年1月至2020年11月期间,对55名接受过使用异构骨移植进行重建手术的接受者进行了回顾性观察性研究.
- 移植物是从手术残留物中获取的,单独移植或用植入物/水泥增强.
- 评估的结果包括感染率 (早期,延迟,晚期) 和实现下肢移植重量承载的时间.
主要成果:
- 总共有70个移植;55个接受者在至少一年的随访后被分析.
- 总体感染率为7.2% (4例),其中有2种急性和2种慢性感染.
- 单独使用的移植的平均时间为7个月,增强时为3.5个月.
- 五名患者 (9.1%) 没有完全实现移植整合.
结论:
- 来自手术残留物的异构骨移植在重建性手术中是有效的和令人鼓舞的.
- 使用植入物或水泥增强显著减少了承重时间.
- 这些移植显示出作为生物辅助剂的潜力,改善了重建性手术的结果.
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