孕期糖尿病的妇女在第二个三个月的孕期甲状腺激素评估
Divya Christy1, Jahnavi Chandrasekar1
1Obstetrics and Gynaecology, Sree Balaji Medical College and Hospital, Chennai, IND.
Cureus
|December 31, 2025
概括
甲状腺功能障碍经常与孕期糖尿病 (GDM) 在孕妇中共存,通常是自身免疫性质的. 在GDM患者中早期查甲状腺问题对于改善母亲和胎儿的结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 产科 产科 产科 产科 产科
- 周围生理学 周围生理学
背景情况:
- 怀孕期间甲状腺功能障碍是对孕产妇和胎儿不良后果的未被认可的危险因素.
- 孕期糖尿病 (GDM) 和甲状腺疾病共享重叠的途径,可以放大产科风险,特别是在印度这样缺乏的地区.
研究的目的:
- 为了确定甲状腺功能障碍的患病率,风险因素和围产期影响,在怀孕后的孕妇中与GDM在他们的第二个三个月.
主要方法:
- 一项基于医院的横截面研究涉及105名被诊断患有GDM的孕妇.
- 测量了血清TSH,FT4和抗TPO抗体;使用ATA怀孕特定范围对甲状腺功能障碍进行分类.
- 后勤回归分析了预测因素和结果,p < 0.05被认为是显著的.
主要成果:
- 甲状腺功能障碍,主要是亚临床甲状腺功能低下症,在11.4%的GDM女性中发现.
- 年龄较大,BMI较高,甲状腺疾病家族史和抗TPO阳性与甲状腺功能障碍有关.
- 患有甲状腺功能障碍的妇女需要胰岛素的频率更高,新生儿巨和NICU入院率更高.
结论:
- 甲状腺功能障碍和GDM的同时发生具有临床意义,并且往往是自身免疫性.
- 建议在GDM患者中进行常规查甲状腺功能和抗TPO抗体.
- 早期诊断和干预可以预防产周并发症,改善孕产妇和胎儿的结果.
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