一个务实的并行集群随机试验,以评估优化电子监视器在改善中国结核病患者治疗坚持的实施和有效性:研究协议
Liming Yang1,2,3, Min Su1
1School of Public Management, Inner Mongolia University, Hohhot, China.
Frontiers in public health
|December 31, 2025
概括
这项研究优化了电子监视器和智能手机应用程序 (EM程序),以改善内蒙古的结核病 (TB) 治疗遵守率和健康结果. 加强的EM计划旨在在中国和类似地区实现更广泛的采用.
科学领域:
- 公共卫生 公共卫生
- 实施科学 实施科学
- 数字健康数字健康
背景情况:
- 结核病 (结核病) 治疗的不遵守严重影响了内蒙古的生存率和控制效率.
- 现有的电子监视器和智能手机应用程序 (EM) 程序需要优化以获得更大的影响.
研究的目的:
- 优化电子监视器和智能手机应用程序 (EM) 程序,以改善结核病治疗的坚持和健康结果.
- 开发优化EM计划的干预措施,实施该计划,并计划其扩展.
主要方法:
- 利用实施研究的综合框架来识别EM计划实施的促进者和障碍.
- 采用"实施变革专家建议"协议,为内蒙古环境量身定制战略.
- 进行为期12个月的实用,并行,集群随机试验,以评估优化EM计划对治疗坚持和结核病结果的有效性.
主要成果:
- 主要结果是改善结核病患者的治疗坚持.
- 二级结局包括世卫组织定义的结核病治疗结局:完成率,失去了随访,治疗失败和死亡.
- 该RE-AIM框架将评估干预的覆盖范围,有效性,采用,实施和维持.
结论:
- 这项研究开创了加强结核病治疗坚持和结果的干预措施,在资源有限的环境中制定了可扩展性的策略.
- 干预活动将被纳入常规结核病护理,并由当地负责.
- 预计将进一步了解长期影响,疗效,成本效益和可行性.
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